@article {139,
	title = {Genomic approaches to identification of tumour-susceptibility genes using mouse models.},
	journal = {Curr Opin Genet Dev},
	volume = {13},
	year = {2003},
	month = {2003 Feb},
	pages = {14-9},
	abstract = {<p>Individual susceptibility to cancer in humans is determined by complex interactions between germline genetic variation and levels of exposure to environmental carcinogens or tumour promoters. Only a small fraction of cancer susceptibility is inherited in a Mendelian manner (high-penetrance familial cancer), and most tumours result from the combined effects of many gene-gene and gene-environment interactions. The sequencing of the mouse genome provides new approaches to one of the most challenging tasks of cancer genetics today.</p>},
	keywords = {Animals, Chromosome Mapping, Disease Models, Animal, Genetic Predisposition to Disease, Genomics, Humans, Mice, Neoplasms, Oligonucleotide Array Sequence Analysis, Quantitative Trait Loci},
	issn = {0959-437X},
	author = {Jiang-Hua Mao and Balmain, Allan}
}
